Juvederm XC

The new JUVÉDERM® XC formulation is enhanced for patient comfort. You can now get the smoothness you expect, with the improved comfort you want ‡. JUVÉDERM® XC provides smooth and natural looking results and now a more comfortable experience – so everyone will notice but no one will know! In fact, studies show results of JUVÉDERM® last up to one year.**

As we age, our skin changes. Over time, the natural volume of youthful skin begins to diminish as wrinkles and folds form. But, with JUVÉDERM® injectable gel, you don't have to just sit back and let it happen!

JUVÉDERM® is a smooth consistency gel made of hyaluronic acid – a naturally occurring substance in your skin that helps to add volume and hydration. Your healthcare professional eases JUVÉDERM® injectable gel under the skin to instantly restore your skin's volume and smooth away facial wrinkles and folds, like your “smile lines” or “parentheses” (nasolabial folds – the creases that run from the bottom of your nose to the corners of your mouth).

With Juvéderm™ the injection process takes only about 15 minutes and results are immediate. Plus, there's minimal recovery or downtime. So you can step into the office for treatment and step right back into your life.

* JUVÉDERM® provides smooth and natural looking results.
* JUVÉDERM® is the only hyaluronic acid (HA) filler FDA approved
* to last up to 1 year.
* JUVÉDERM® New JUVÉDERM® XC is now formulated with an anesthetic for a more comfortable patient experience.‡

* With JUVÉDERM® the injection process takes only about 15 minutes and results are immediate. Plus, there’s minimal recovery or downtime. So you can step into your doctor’s office for treatment and step right back into your life. And now with the newest formulation of JUVÉDERM®, the effects of lidocaine take place in seconds, potentially reducing the need for further anesthetic.†

*In the United States, JUVÉDERM® injectable gel is indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).

**Pinsky MA, Thomas JA, Murphy DK, Walker PS; for JUVÉDERM® vs. ZYPLAST® Nasolabial Fold Study Group. Juvederm injectable gel: A multicenter, double-blind, randomized study of safety and effectiveness. Aesthetic Surg J. 2008:28(1):17-23.

‡Compared to the non-lidocaine JUVÉDERM® formulation.

†Data on file, Allergan, Inc.; Weinkle SH, Bank DE, Boyd CM, Gold MH, Thomas JA, Murphy DK. A multi-center, double-blind, randomized controlled study of the safety and effectiveness of JUVÉDERM® injectable gel with and without lidocaine. J Cosmet Dermatol. 2009;8(3):205-210. Please see JUVÉDERM® Ultra XC and JUVÉDERM® Ultra Plus XC Patient Safety Information for more information.

JUVÉDERM® is part of the Allergan portfolio of products and this is the JUVÉDERM® website. For information on BOTOX® Cosmetic, visit www.botoxcosmetic.com. JUVÉDERM® Safety Information *JUVÉDERM® is indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds). Important JUVÉDERM® Safety Information JUVÉDERM® injectable gel (including JUVÉDERM® Ultra, JUVÉDERM® Ultra Plus, JUVÉDERM® Ultra XC, and JUVÉDERM® Ultra Plus XC) is indicated for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds). Side effects were usually mild to moderate, lasting 7 days or less, and included temporary injection-site reactions such as redness, pain, firmness, swelling, and bumps. JUVÉDERM® is not for people with severe allergies. For more information, please click on the About Safety link at www.juvederm.com or call the Allergan Product Support line at 1-877-345-5372. JUVÉDERM® injectable gel is available by prescription only. BOTOX® Cosmetic Important Information Indication BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults younger than 65 years of age for a short period of time (temporary). IMPORTANT SAFETY INFORMATION, INCLUDING BOXED WARNING BOTOX® Cosmetic may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX® Cosmetic: * Problems swallowing, speaking, or breathing, due to weakening of associated muscles, can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months. * Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice (dysphonia), trouble saying words clearly (dysarthria), loss of bladder control, trouble breathing, trouble swallowing. There has not been a confirmed serious case of spread of toxin effect when BOTOX® Cosmetic has been used at the recommended dose to treat frown lines. Do not take BOTOX® Cosmetic if you: are allergic to any of the ingredients in BOTOX® Cosmetic (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc® or Dysport™; have a skin infection at the planned injection site. Tell your doctor about all your muscle or nerve conditions such as such as amyotrophic lateral sclerosis [ALS or Lou Gehrig's disease], myasthenia gravis or Lambert-Eaton syndrome as you may be at increased risk of serious side effects including severe dysphagia (difficulty swallowing) and respiratory compromise (difficulty breathing) from typical doses of BOTOX® Cosmetic. Tell your doctor about all your medical conditions, including if you have: plans to have surgery; had surgery on your face; weakness of forehead muscles, such as trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (It is not known if BOTOX® Cosmetic can harm your unborn baby); are breast-feeding or plan to breastfeed (It is not known if BOTOX® Cosmetic passes into breast milk). Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins and herbal products. BOTOX® Cosmetic may cause loss of strength or general muscle weakness, or vision problems. If this happens, do not drive a car, operate machinery, or do other dangerous activities. Other side effects of BOTOX® Cosmetic include: dry mouth, discomfort or pain at the injection site, tiredness, headache, neck pain, and eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids, swelling of your eyelids, and dry eyes. For more information refer to the Medication Guide or talk with your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. Please see BOTOX® Cosmetic Full Product Information including Medication Guide.